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Diabetes Can Be Detected Simply by Breathing

Globally, 43% of people with diabetes (around 252 million individuals) are unaware that they suffer from this condition. In many cases, the diagnosis is delayed, as traditional tests require time, resources, and a visit to a medical facility.

Now, diabetes can be detected through breathing. And this is only the beginning.

A New Breath Sensor: Diagnosis Without a Laboratory

A research team led by Associate Professor of Engineering Huanyu “Larry” Cheng at Penn State University has developed a sensor that can determine diabetes and prediabetes in just a few minutes from a breath sample. The study's results were published in the Chemical Engineering Journal.

The procedure is simple: a breath sample is collected in a special bag, which is then brought into contact with the sensor, and the result is obtained within minutes. No blood test or laboratory examination is required.

What Is Acetone and Why Is It in Our Breath?

Traditional diabetes tests measure blood glucose levels, but this new technology takes a different approach: it analyzes acetone in the breath.

Acetone is a natural substance formed during fat breakdown. It is also present in small amounts in the breath of healthy individuals. But when the level rises above one part in 1.8 million, it indicates a risk of diabetes.

Why Is This Small Device So Smart?

The sensor’s effectiveness comes from the materials used in its construction. To create it, researchers employed laser-induced graphene — a porous graphene layer formed by laser on a polyimide film, capable of capturing gas molecules.

However, graphene alone is not selective enough to distinguish acetone from other gases. That is why zinc oxide was added to the material. This combination makes the sensor sensitive only to acetone while ignoring other substances.

Another challenge was the high humidity in the breath: water molecules could displace acetone and distort the results. To solve this, researchers added a selective membrane — a special layer that blocks water but allows acetone to pass through.

What Could This Technology Become in the Future?

Currently, the device requires collecting a breath sample in a special bag. But the next step is to design a sensor that can be placed directly under the nose or integrated into a mask.

The most exciting part is that this technology could be used not only for the early detection of diabetes but also for personalized health monitoring. Acetone levels are influenced by diet, physical activity, and lifestyle. This means that in the future, the sensor could show you:

  • How suitable is your diet?
  • How your exercise program affects your body.
  • Even though fasting or carbohydrate intake impacts your system.

“If we can understand how acetone levels change with diet and physical activity, this technology could create great opportunities not only for diagnostics but also for daily health monitoring,” emphasizes Larry Cheng.

Is a Future Without Needles for Diagnosis Possible?

With this technology:

  • People will be able to monitor their health without pain or discomfort.
  • Diabetes risk can be detected in advance.
  • Diabetic complications will be reduced or prevented.
  • Health monitoring will become more accessible and personalized.

The project is funded by the U.S. National Institutes of Health (NIH) and the National Science Foundation (NSF). The team is already working on a commercial version of the device.
Preventing diabetes may be as close as a single breath.

Source:   New breath sensor detects diabetes quickly and easily - sciencedaily.com